产品货号：
Z28698
中文名称：
TPSAB1抗体
英文名称：
Anti-TPSAB1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TPSAB1 Antibody |
| 指标别名 | MCP7;TPS1;TPS2;TPSAB1;TPSB1;Tryptase 1;tryptase alpha/beta 1;Tryptase beta 1;Tryptase I |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | IHC |
| 基因名称 | TPSAB1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human Mast Cell Tryptase recombinant protein (Position:H65-P275).Human Mast Cell Tryptase shares 77% and 76.1% amino acid (aa) sequence identity with mouse and rat Mast Cell Tryptase,respectively. |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Tryptase alpha-1 and tryptase beta-1 are enzymes that in humans are encoded by the same TPSAB1 gene.Tryptases comprise a family of trypsin-like serine proteases,the peptidase family S1.Tryptases are enzymatically active only as heparin-stabilized tetramers,and they are resistant to all known endogenous proteinase inhibitors.Several tryptase genes are clustered on chromosome 16p13.3.These genes are characterized by several distinct features.They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability.In addition,these genes have an intron immediately upstream of the initiator Met codon,which separates the site of transcription initiation from protein coding sequence.This feature is characteristic of tryptases but is unusual in other genes.The alleles of this gene exhibit an unusual amount of sequence variation,such that the alleles were once thought to represent two separate genes,alpha and beta 1.Beta tryptases appear to be the main isoenzymes expressed in mast cells;whereas in basophils,alpha tryptases predominate.Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. |
| Uniprot ID | Q15661 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | tryptase alpha/beta 1 |
| 蛋白名全称 | Tryptase alpha/beta-1 |
| 推荐稀释比 | Immunohistochemistry in paraffin section IHC-(P) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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